New publications, news, events and downloads

To help keep up to date with developments we have compiled a list of recent publications, news items and upcoming events relevant to health economic diabetes simulation modeling.

If you would like to post publications, news or events please follow this link.

Most recent posting:  8 August 2019

Models and methods

Cornerstone Diabetes Simulation Model Validation published. New diabetes model based UKPDS Outcomes Model has carried out an extensive external validation exercise.

Modeling of Diabetes and Its Clinical Impact  Review of diabetes models including recent developments in In Silico modelling. 

Novel Risk Engine for Diabetes Progression and Mortality in USA: Building, Relating, Assessing, and Validating Outcomes (BRAVO)  Provides an alternative to the UKPDS risk engine to assist clinical and policy decision making such as cost-effective resource allocation in USA.

Computer Modeling of Diabetes and Its Transparency: A Report on the Eighth Mount Hood Challenge Proceedings of the 2016 Mt Hood Conference now published in Value in Health. New Guidelines for transparency in simulation modeling. 

Quality of life & diabetes

New studies estimating the impact complications have on quality of life using preference based measures such as the EQ-5D and SF-6D. 

NEW Minimally Important Difference of the EQ-5D-5L Index Score in Adults with Type 2 Diabetes Value in Health Early Online. MID estimates ranged between 0.03 and 0.05.

Do Country-Specific Preference Weights Matter in the Choice of Mapping Algorithms? The Case of Mapping the Diabetes-39 onto Eight Country-Specific EQ-5D-5L Value Sets. Quality of Life Research. The D-39 can be mapped onto the EQ-5D-5L utilities with good predictive accuracy.

Costs of diabetes and its treatments

NEW Medical Costs of Patients with Type 2 Diabetes in a Single Payer System: A Classification and Regression Tree Analysis Italian study looking at ways to classify the costs of people with diabetes.

Treatment choice, medication adherence and glycemic efficacy in people with type 2 diabetes: a UK clinical practice database study For patients with type 2 diabetes, increasing medication adherence can bring about meaningful improvements in HbA1c control as the requirement for treatment escalation increases. 

Economic Burden of Cardiovascular Disease in Type 2 Diabetes: A Systematic Review, New paper in value in health provides complication costs.

Direct medical costs of diabetes mellitus in the year of mortality and year before mortality. The analysis provides new evidence on incorporating additional direct medical costs in the mortality year for use in costing and cost-effectiveness analyses of interventions for DM.

Health Care Costs Associated With Incident Complications in Patients With Type 2 Diabetes in Germany New cost estimates for complications of diabetes based on very large insurance data set from Germany involving 316,220 people with type 2 diabetes. Overview in a recent blog

Recent applications

NEW Cost‐Effectiveness of a Community‐Based Diabetes Prevention Program with Participation Incentives for Medicaid Beneficiaries Community‐based DPP has the potential to reduce diabetes and cardiovascular‐related morbidity and mortality for low‐income persons and may be a cost‐effective investment for Medicaid programs.

NEW Cost-effectiveness of the 2014 U.S. Preventive Services Task Force (USPSTF) Recommendations for Intensive Behavioral Counseling Interventions for Adults With Cardiovascular Risk Factors US Task Force recommended intervention is cost effective based on the conventional CE threshold, but prioritization based on risk level would yield larger total health gains per dollar spent.

Economic Value of Improved Accuracy for Self-Monitoring of Blood Glucose Devices for Type 1 and Type 2 Diabetes in England Investment in devices with higher strip prices but improved accuracy (less error) appears to be an efficient strategy for insulin-treated diabetes patients at high risk of severe hypoglycemia.

Health Policy

NEW Individualized Glycemic Control for U.S. Adults With Type 2 Diabetes: A Cost-Effectiveness Analysis Ann Intern Med. 2017. Health policies and clinical programs that encourage an individualized approach to glycemic control for U.S. adults with type 2 diabetes reduce costs and increase quality of life compared with uniform intensive control. 

Proposed fee schedule details for Diabetes Prevention Program payments Plans to boost US Medicare  coverage of diabetes prevention and telehealth services.

Strategies to Prioritize Clinical Options in Primary Care Using diabetes models to assist clinicians in determining what interventions make a difference to long-term outcomes of their patients. 

In the news...

NEW Online simulator helps diabetes patients understand the impact of exercise on blood glucose A new app developed by researchers at the University of Utah may be a tool for helping people living with diabetes. 

Mathematical model can simulate HbA1c progression in T2DM Phil McEwan, Ph.D., from Health Economics and Outcomes Research Ltd. in Cardiff, U.K., and colleagues developed an alternative MM to simulate HbA1c progression in T2DM.

Gum disease self-maintenance for type 2 diabetes is ‘cost effective’ A study that uses the Core Diabetes Model quoted in a recent news item.

 

Presentations and events

NEW Mt Hood Asia regional meeting to be held in Seoul Korea 30 Nov-1 Dec 2019

Next Mt Hood challenge will be hosted by the University of Chicago and will be held after the American Diabetes Association Congress in June 2020.  

Selected presentations from 2018 Mt Hood challenge available.

Excel- Cost calculator for estimating the cost of diabetes complications in Australia

Framingham Risk Calculator Calibrated for Indigenous Australians

Meta-model for predicting average QALY change from diabetes simulation models

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