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Utility values for diabetes models

The list below reports utilities that have been developed specifically for health states relevant to diabetes simulation models. Please contact us if you know of additional studies that could be added to the table via the Mt Hood Network email (mthood2016[at]

Meta-analyses and systematic reviews

Lung TWC,. Hayes,AJ, Hayen A, Farmer A & Clarke PM.A meta-analysis of health state valuations for people with diabetes: Explaining the variation across methods and implications for economic evaluation, Quality of Life Research 20(10):1669 (2011) PMID 21472392

Beaudet, A. Clegg, J. Thuresson, PO. Lloyd A. and  McEwan P. Review of Utility Values for Economic Modeling in Type 2 DiabetesValue in Health, 2014, Volume 17, Number 4, Page 462 DOI: 10.1016/j.jval.2014.03.003

Smith-Palmer,J. Bae, JP Boye,KS. Norrbacka, K. Hunt,B. and Valentine WJ Evaluating health-related quality of life in type 1 diabetes: a systematic literature review of utilities for adults with type 1 diabetesClinicoecon Outcomes Res. 2016; 8: 559–571.

Individual studies (by year of publication)

Coffey JT, Brandle M, Zhou H, et al. Valuing health-related quality of life in diabetes. Diabetes Care 2002;25:2238-2243.

Clarke P, Gray A, Holman R. Estimating Utility Values for Health States of Type 2 Diabetic Patients Using the EQ-5D (UKPDS 62). Med Decis Making. 2002 Jul-Aug;22(4):340-9.  

Bagust & Beale. Modelling EuroQol Health-related Utility Values for Diabetic Complications from CODE-2 data. Health Econ. 2005 Mar;14(3):217-30. 


Currie CJ, Morgan CL, Poole CD, Sharplin P, Lammert M, McEwan P. Multivariate Models of Health-related Utility and the Fear of Hypoglycaemia in People with Diabetes. Curr Med Res Opin. 2006 Aug;22(8):1523-34.

Dennett SL, Boye KS, Yurgin NR. The Impact of Body Weight on Patient Utilities with or without Type 2 Diabetes: A Review of the Medical Literature. Value Health. 2008 May-Jun;11(3):478-86.

Hayes, AJ Clarke, PM. Voysey M. and Keech A.  Simulation of quality adjusted survival in chronic diseases: an application in type 2 diabetes Medical Decision Making, 2011 Jul-Aug;31(4):559-70.

Heintz E, Wiréhn AB, Peebo BB, Rosenqvist U, Levin LÅ. QALY Weights for Diabetic Retinopathy—A Comparison of Health State Valuations with HUI-3, EQ-5D, EQ-VAS, and TTO. Value Health. 2012 May;15(3):475-84.

Zhang P, Brown MB, Bilik D, Ackermann RT, Li R, Herman WH. Health utility scores for people with type 2 diabetes in U.S. managed care health plans: results from Translating Research into Action for Diabetes (TRIAD). Diabetes Care 2012;35:2250-2256.

Evans M, Khunti K, Mamdani M, Galbo-Jørgensen CB, Gundgaard J, Bøgelund M, Harris S. Health-related Quality of Life Associated with Daytime and Nocturnal Hypoglycaemic Events: A Time Trade-off Survey in Five Countries. Health Qual Life Outcomes. 2013 Jun 3;11:90. DOI: 

Alva M, Gray A, Mihaylova B, Clarke P. The effect of diabetes complications on health-related quality of life: the importance of longitudinal data to address patient heterogeneity. Health Econ 2014 Apr;23(4):487-500.. 

Lane S, Levy AR, Mukherjee J, Sambrook J, Tildesley H. The impact on Utilities of Differences in Body Weight among Canadian Patients with Type 2 Diabetes. Curr Med Res Opin. 2014 Jul;30(7):1267-73.

Burström K, Sun S, Gerdtham UG, Henriksson M, Johannesson M, Levin LÅ, Zethraeus N. Swedish Experience-based Value Sets for EQ-5D Health States. Qual Life Res. 2014 Mar;23(2):431-42.

Shingler S, Fordham B, Evans M, Schroeder M, Thompson G, Dewilde S, Lloyd AJ. Utilities for Treatment-related Adverse Events in Type 2 Diabetes. J Med Econ. 2015 Jan;18(1):45-55.

Chen G, Iezzi A, McKie J, Khan M, Richardson J. Diabetes and Quality of Life: Comparing Results from Utility Instruments and Diabetes-39. Diabetes Research and Clinical Practice, 2015, 109 (2): 326-333. DOI: 10.1016/j.diabres.2015.05.011. 

Hayes, A. Arima, H. Woodward, M. Chalmers, J. Poulter, N. Hamet, P. Clarke, P. (2016) Changes in Quality of Life Associated with Complications of Diabetes: Results from the ADVANCE Study, Value in Health, 19(1), 36-41.

Jiao F, Wong CKH, Gangwani R, Tan KCB, Tang SCW, Lam CLK. Health-related quality of life and health preference of Chinese patients with diabetes mellitus managed in primary care and secondary care setting: decrements associated with individual complication and number of complications. Health Qual Life Outcomes. 2017 Jun 13;15(1):125. 

Briggs AH, Bhatt DL, Scirica BM, Raz I, Johnston KM, Szabo SM, Bergenheim K, Mukherjee J, Hirshberg B, Mosenzon O. Health-related quality-of-life implications of cardiovascular events in individuals with type 2 diabetes mellitus: A subanalysis from the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus (SAVOR)-TIMI 53 trial. ​Diabetes Res Clin Pract. 2017 Aug;130:24-33. 

Matza LSBoye KSStewart KDDavies EWPaczkowski RHealth state utilities associated with attributes of weekly injection devices for treatment of type 2 diabetes. BMC Health Services Research 201717:774.

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